Hi Boaz. Your city may have laws that prohibit businesses in residential areas. Zoning laws are different across countries, cities, and even streets. I saw a case in France where one house was perfectly fine for a business and the one next door was not.
You would need to ask your local zoning commission if the house at a particular address could be used for commercial purposes. If you don't have a specific property in mind yet, pick one that could potentially be an option and ask about that one. At least it will give you an idea of what kind of restrictions apply.